I bought these two together as they seemed to complement one another. I have to say, they do seem to make a difference. Now, to be honest, I don't always notice a big difference while taking them all the time. My system is to take them 5 days/week, nothing over the weekend, and start up again on Monday. Where I notice the difference is when I come back to them on Monday...they make me feel much more comfortable, sharper in mind, and just an overall well being. I have taken these products from others, but have never been able to feel this kind of actual difference, so obviously, I will stick with these products.